autophagosome

Autophagy induced by aminophylline in peripheral blood T lymphocytes;

氨茶堿誘導T淋巴細胞自噬現象的觀察

Induction mechanisms of autophagy and its role in cancer therapy;

自噬的誘導機制及其在腫瘤治療中的作用

Research Progress on Autophagy Molecule Mechanism;

自噬分子機制的研究進展

A novel path for therapy of neural degeneration diseases is offered by the application of small molecule,which enhances the clearance of aggregate-prone proteins through inducing autophagy.

大量突變和錯誤折疊的蛋白質在細胞內聚集是神經退行性疾病產生的基礎,研究發現一些小分子可以通過引起細胞自噬而降解細胞內聚集的突變蛋白,為治療神經退行性疾病提供了新的方法。

Autophagy is a common,functionally and evolutionarily preserved p.

但是,關于其細胞自噬基因的研究目前還未見報道。

[Objective] To investigate the function of the hAPG12 in the process of autophagy in yeast, the hAPG12-EGFP fusion gene shuttle vector was constructed and The plasmid constructed above was transformed into the yeast.

結果證實EGFP-hAPG12基因已完全正確亞克隆到pESC-URA中,熒光顯微鏡觀察結果證明EGFP-hAPG12融合蛋白在酵母中成功表達,以誘導培養24h的熒光最強,EGFP-hAPG12定位于酵母的自噬體中。