ubiquitin

Ubiquitin - proteasome pathway is a highly effective protein - degradation pathway in the eukaryotic cells.

泛素 - 蛋白酶體途徑是真核細胞內一種高效蛋白降解途徑.

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Skp 2 is an Fbp, which targets many ubiquitin - mediated degradation of G 1 - and S - phase regulators.

研究表明許多惡性腫瘤中存在著Skp2相關機制的異常, Skp2現已被認為是一種重要的癌基因.

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So abnormality of the ubiquitin - proteasome proteolytic pathway is closely related to many diseases, especially cancer.

泛素介導的蛋白質降解途徑的異常與許多疾病特別是腫瘤的發生密切相關.

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Conclusion: GFPu - 1 clonal cells may be a sensitive indicator for the function of the ubiquitin - proteasome system.

結論: GFPu -1 克隆細胞是一種反映UPS功能的敏感指標.

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The mRNA expression of ubiquitin in rat EDL muscle was determined by northern blot analysis.

應用northernblot方法測定伸指長肌組織泛素mRNA的 表達變化,分析骨骼肌蛋白降解與泛素mRNA表達的關系.

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