(2S,3S,5S)-2,5-Diamino-3-hydroxy-1,6-diphenylhexane, the key intermediate of lopinavir was synthesized from L-phenylalanine by N,O-benzylation, cyanidation, Grignard reaction and reduction to give (2S,3S,5S)-5-amino-2-dibenzylamino-1,6-diphenylhexan-3-ol, which was subjected to debenzylation with an overall yield of about 63%.
L-苯丙氨酸用氯芐進行N,O-芐基化、氰化、格氏反應、還原制得(2S,3S,5S)-5-氨基-2-二芐胺基-1,6-二苯基-3-己醇,再經鈀炭催化脫芐制得抗病毒藥洛匹那韋中間體(2S,3S,5S)-2,5-二氨基-3-羥基-1,6-二苯基己烷,總收率約為63%。
Study on the Synthesis of the Core Unit of Ritonavir and Lopinavir;
抗艾滋病藥物利托那韋和洛匹那韋核心結構的合成研究
he is a small beast from Lower Boulonnais.
那是一匹下布洛涅種的小牲口。
The rest of the field is / are far behind Shalock.
其余的馬都遠遠落在名叫夏洛克的那匹馬后面。
Simultaneous and Rapid Determination of Aciclovir, Ganciclovir and Penciclovir in Plasma Using Solid-phase Extraction and High-performance Liquid Chromatography;
SPE-HPLC法同時快速測定血漿中更昔洛韋、阿昔洛韋和噴昔洛韋的濃度
Dumfries & Galloway
阿鄧弗里斯-蓋洛韋
Ms. Galloway works in the nation's capital.
加洛韋女士在首都工作,
Mallory - Weiss syndrome
馬洛萊-韋斯征候群
Comparison of Effects of Ganciclovir and Acyclovir on Adult Varicella
更昔洛韋和阿昔洛韋治療成人水痘的療效比較
Method for determining ganciclovir quantity contained in ganciclovir cream
更昔洛韋乳膏中更昔洛韋含量測定方法的研究
Therapeutic effects of ganciclovir and aciclovir on varicella
更昔洛韋與阿昔洛韋治療水痘臨床療效分析
But not to worry: it all . . . falls into place in the book's second half, where the language is plainer(Hallowell Bowser)
但別擔心:它全都在書的后半部分,那兒的語言淺顯一些(哈洛韋爾 鮑瑟)
A HPLC method was established for the determination of Aciclovir in Aciclovir urea cream.
建立阿昔洛韋尿素乳膏中阿昔洛韋含量的HPLC測定方法。
In 153 cases of prevention research,88 were in GCV group and 65 in ACV group;
預防研究共153例,更昔洛韋組88例,阿昔洛韋組65例。
Objective:To investigate the clinic response of genital herpes (GH) treated by acyclovir (ACV) and valacyclovir(VCV).
目的:觀察阿昔洛韋與萬乃洛韋治療生殖器皰疹的臨床療效。
Objective:To investigate the clinic response of herpes zoster (HZ) treated by acyclovir (ACV) and valacyclovir (VCV).
目的:觀察阿昔洛韋與萬乃洛韋治療帶狀皰疹的臨床療效。
Research of Antiviral Activity of Ganciclovir and Acyclovir to Varicella-zoster Virus in Vitro;
更昔洛韋與阿昔洛韋體外抗水痘—帶狀皰疹病毒活性的研究
Content determination of ganciclovir in Ganciclovir Sodium Chloride Injection by UV
紫外分光光度法測定更昔洛韋氯化鈉注射液中更昔洛韋的含量
Determination the Content of Ganciclovir in Ganciclovir Gel by HPLC
高效液相色譜法測定更昔洛韋凝膠劑中更昔洛韋的含量
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